From bacteria to eukaryotes, cells have evolved a remarkable battery of enzymes to deal with the mechanical and topological challenges presented by nucleic acid production, processing and maintenance. A clear view of the biology of the genetic material requires a molecular understanding of how these enzymes function. Such an understanding will enhance our ability to manipulate genome structure and gene expression. The theme of this meeting revolves around the mechanisms of these enzymes, with particular emphasis on research that integrates structural, biochemical, biophysical and computational approaches. With recent technological advances in imaging (i.e., single-molecule and cryo-electron microscopies), we expect to witness a flourish of key biological systems to be characterised with unprecedented detail.

This meeting will cover many of the molecular mechanisms by which large macromolecular machines carry out a diverse range of nucleic acid processes including DNA replication and repair, gene transcription and regulation, RNA processing and splicing, translation, nucleic acids structures and chromatin structure and epigenetic mechanisms. The meeting will also explore new quantitative techniques as well as theoretical approaches.

This meeting is being organised by the Biochemical Society in collaboration with NVBMB (The Netherlands) and SEBBM (Spain) as a FEBS 3+ meeting.

The FEBS3+ Meetings programme was established by FEBS to support scientific meetings, organised through collaboration of at least three FEBS Constituent Societies. The aim of the programme is to increase international collaboration between molecular life scientists in a subset of countries within the FEBS area, while also encouraging sharing of expertise and efforts. These events are generously supported by FEBS.

A FEBS3+ travel award scheme is also available to young scientists living outside the host country, who are members of the collaborating Societies. More information to follow.

For further details and to book please visit the Biochemical Society website

Continuing Professional Development (CPD)

This event is approved by the Royal Society of Biology for purposes of CPD and may be counted as 120 CPD credits.