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Date
22.08.22 - 25.08.22
Department of Biochemistry, South Parks Road, Oxford

Overview

The programme is designed to provide training for early career researchers for upskilling and capacity building in ageing biology research. The course includes lectures presented by world experts, as well as group workshops on critical appraisal of the published literature, and hands-on molecular biology and bioinformatics classes. The course is designed to build understanding and skills in steps along the drug discovery pipeline in ageing research by covering (sequentially) the basic biology of ageing processes, biomarkers and targets, tools in target identification and screening (including spatial and single cell -omics), through to drug discovery and clinical trials, including the regulatory and ethical framework as well as showcasing examples of clinical trials. The summer school is designed to provide an opportunity for genuine networking as well as skills training, with an agreement in principle with the publisher Springer to publish 6-8 reviews arising from the workshop in the journal Advances in Gerontolgy to increase dissemination of ageing biology and support career progression of early career researchers.   
Ageing biology is a relatively new field that is rarely taught on undergraduate courses in the UK. UKRI (BBSRC and MRC) identified a need for capacity building in the field and have funded the UK Ageing Network (www.UKANet.org.uk) of which BLAST is a member network (I am co-director of both BLAST and UKANet). Our goal is to provide training in relevant skills and tools, networking opportuntites to break down artificial barriers between dsicplines in the field, promote dissemination of ageing research and aid career progression for early career researchers. A key part of our delivery plan is to run this immersive summer school in our topic area ie ageing science and translation.


Learning Outcomes

By the end of the course, we expect that all delegates will have achieved the learning outcomes of: (1) Increased knowledge of the following: The changing demographics of global populations, and the contribution of biological ageing processes to diseases of ageing and multimorbidity; the geroscience hypothesis, and hallmarks of ageing including cell senescence; targeting aspects of senescence and ageing biology to improve health; the use of modern molecular tools and -omics to study ageing biology, including state of the art spatial transcriptomics and single cell sequencing; modes of drug discovery including target-based and phenotypic screening; regulatory frameworks for clinical trials; examples of drug discovery and clinical trials in ageing. (2) Acquired new skills (and/or received refresher training) through hands-on experience using age-relevant examples in: critical appraisal of the ageing research literature; homology searching for genes/RNA and protein sequences using online databases; PCR primer design; in silico cloning; differential gene expression analysis for biomarker/target identification using online tools.

Continuing Professional Development (CPD)

This event has been approved by the Royal Society of Biology for purposes of CPD and can be counted as  66 CPD points.

Further information and booking

For more information, including a registration form and event fees, visit the BLAST research network's event page. Please be advised that the programme timings, lecture titles and speakers may be subject to change.