A Biochemical Society Scientific Meeting
Membrane proteins carry out many essential biological functions and due to their importance in biology constitutes the primary targets for more than half of known drugs. Recent advances in both the instrumentation and MS-based methodologies have enabled its application to the challenging membrane-resident assemblies. These highly heterogeneous and dynamic assemblies are often difficult to study by traditional structural approaches - structural mass spectrometry offers a novel alternative. The use of mass spectrometry based techniques to study membrane proteins is recent and has sparked considerable interest from the biochemical community, eager to understand the specifics of techniques previously used mainly as analytical tools. Therefore, a scientific meeting with such a focus on the ever-growing developments and applications of structural mass spectrometry of membrane proteins and their complexes will be very much appreciated by the society and attract a lot of interest beyond mass spectrometry. Moreover, this event is timely due to its application to a wide range of biological systems currently difficult to tackle by other approaches. In particular, the application of HDX-MS on membrane proteins consists of an entirely new subject not covered by any meetings in the UK currently.
This two-day meeting aims to bring together structural mass spectrometry experts to present their work on the field of membrane proteins, as well as structural biologists curious to learn more about these methods.
The topics will cover the latest developments in instrumentation, intact membrane protein complexes, data analysis, software development and a range of applications to membrane proteins, such as lipid and drug interactions, dynamics of transporters and channels, membrane protein folding, and the study of large macromolecular complexes.
Continuing Professional Development (CPD)
This event is approved by the Royal Society of Biology for purposes of CPD
and may be counted as 60 CPD credits