A British Society of Toxicological Pathology (BSTP) meeting
The BSTP's 36th Annual Scientific Meeting will cover the topic of pathology of mice with human immune systems (HIS mice).
Immunodeficient mice reconstituted with a human immune system are increasingly used for modelling the human immune compartment in numerous preclinical applications, such as adoptive cell therapy and immuno-oncology studies. With the advent of new Advanced Therapy Medicinal Products, humanised mice are likely to become more and more a key component of efficacy and safety assessment in preclinical programmes, including GLP studies. However, limited information is available concerning the morphological aspects of human cell engraftment and the spectrum of spontaneous and experimentally-induced histopathological lesions occurring in these mice.
Working with the Pathological Society of Great Britain and Ireland, the meeting will cover the main features of the different humanised mouse platforms; their experimental applications in drug development, oncology and gene and cell therapies; specific safety and regulatory considerations; and future promise and remaining challenges.
Opportunities for Trainees/Early Career PathologistsThe BSTP are able to offer three (free place) bursaries for this meeting with applications invited from interested members and non-members of the BSTP.
DeadlinesApplications for the bursary will close at midnight on 24th September 2021.
Early bird registration closes at midnight on 30th September 2021.
Registration will close at midnight on 22nd October 2021.
Continuing Professional Development (CPD)
This event has been approved by the Royal Society of Biology for the purpose of CPD
and may be counted at 30 CPD points.